Strictly speaking this is not an airport hotel, being located in central Manhattan, being located on 4th Avenue / E 13th Street.
As the crow flies its about 7 miles from the centre of the two LGA runways, but I was pleasantly surprised to be able to get a good view of some traffic in and out of LGA.
It's important to point out - Do not book this if you want an airport hotel, but if you do end up in Manhattan on a non spotting trip, this will provide at least some view.
Room plan
To see anything, you'll need to be in a high room, 10th or 11th floor, City view. I was allocated room 1013, facing north which is shown in the plan below with the dot.
From this room, to the left, looking west I could see traffic on its back leg for runway 04 as it travelled south down the Hudson River. I couldn't see anything on finals due to buildings being in the way. I could also see some outbound traffic, east to west.
The east facing rooms, on the left of the plan should give a view of finals to 04. These rooms would be 1001,3,5,7,9,10 and 11. Room 1011 is the corner room on the bottom right of the image.